Undenatured Collagen has a 400x smaller dose than collagen peptides

While collagen peptides have been well-known and abundant in the market for some time, a new category of collagen called Undenatured Type II Collagen is rising in popularity for its research-backed results for improving joint pain. Undenatured Type II Collagen's unique mechanism of action allows it to have a recommended dose that is more than 400x smaller than the standard dose for collagen peptides. 

Undenatured Type II Collagen derived from salmon has shown in human studies to be effective in reducing knee pain in healthy adults at a dose as small as 10mg a day. Undenatured Type II Collagen and undenatured proteoglycan are the two building blocks of our joint cartilage. In its native form, undenatured type II collagen contains two active sites on the protein that are recognized by our body when we orally ingest it. When our gut recognizes these active sites it initiates oral tolerance, which in this case means our immune system learns to stop incorrectly attacking the joint cartilage. This signal to stop the autoimmune attack on the joint cartilage may help reduce inflammation, which many times is the cause of joint pain and discomfort. Collagen peptides do not initiate this oral tolerance response since the active sites of the protein have been broken down.

Studies have shown that undenatured proteoglycan also has a similar oral tolerance effect that helps to reduce pain in the joints as well. 

SCP-II® is 40% undenatured collagen and 40% undenatured proteoglycan and only requires a dose of 25mg/day for joint health benefits.